IPSR - Ideopathic Partial Sex Reversal.
This one reported by a surgeon in the US. A teenager this time.
All other previous cases have been in their 40's. All have been TS though, and this one doesn't break the pattern.
So we have 4 Types, at least.
Type I - Caused by inexplicable prolactin excess, not caused by a prolactemia in the pituitary. Takes about 7 years a age ~45. Kathy Noble is the only case that is documented.
Type II - By far the most common, many cases. Mechanism unknown. Appears to be associated with rapid metabolism of oestrogen. Takes about 2-3 years at age ~45.
Type III - Mechanism appears to be "perfect storm" of two common mutations, triggered by administration of a statin. Takes about 3 MONTHS at age ~45. One known case - me
Type IV - No details yet, but case is in her teens.
Still nothing on PubMed. There's good reason to think this is severely under-reported, especially if it affects men (and that would usually be fatal, I think).
Intermittent postings from Canberra, Australia on Software Development, Space, Politics, and Interesting URLs.
And of course, Brains...
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Monday 24 September 2007
6 comments:
Anonymous commenters - please add a signature (doesn't have to be your real name) on each post of yours. Anne O'Namus, Norm D. Ploom, Angry from Kent, Demosthenes, or even your real initials, it doesn't matter.
Commenters are expected to be polite to each other, but the same standard doesn't apply to comments regarding me.
Australian commenters are very very strongly advised to publish anonymously. Sydney alone has more defamation actions than the entire USA and UK. Nearly double that of the UK in fact.
As Google does not reliably inform me that a comment has been posted, and I have no control over first publication, I assert that all comments are innocently disseminated under the NSW DEFAMATION ACT 2005 - SECT 32 and similar acts.
We always knew you were exceptional... :-\
ReplyDelete---Laserlight
I used to take something of a perverse pride in that.
ReplyDeleteNow... it would be nice to be an ordinary woman.
Not gonna happen, so I guess I'll have to be an extraordinary one.
It would have been nice though.
There's always your next life. :)
ReplyDeleteZoe, do you have a URL for any kind of report on this case?
ReplyDeleteSorry, no report as yet. There's nothing in PubMed about either Kathy Noble's case or mine either.
ReplyDeleteYou are an extraordinary woman!
ReplyDelete