An interesting and productive dialogue has been going on over at the Catholic Answers Forum. There's a number of threads of interest-
Transsexualism - why is it so despised?
What is the Church's position on the Intersexed and Transsexed?
Sex-change: Hypothetical situation
Is transgender a sin?
Theology of the Body--as it relates to transgender
Overcoming Transgender Issues
Apart from the usual misconceptions and misinformed opinion, in general TS and IS people have been treated far more respectfully there than on many other religious forums. We've reached a few people. Now if they weren't so rabidly homophobic... oh well, we're trying to deal with that too. Difficult when we're straight, with a touch of homophobia ourselves too. Some of us. I think mine is now mainly a thing of the past. I hope so, anyway.