Another Case

IPSR - Ideopathic Partial Sex Reversal.

This one reported by a surgeon in the US. A teenager this time.

All other previous cases have been in their 40's. All have been TS though, and this one doesn't break the pattern.

So we have 4 Types, at least.

Type I - Caused by inexplicable prolactin excess, not caused by a prolactemia in the pituitary. Takes about 7 years a age ~45. Kathy Noble is the only case that is documented.

Type II - By far the most common, many cases. Mechanism unknown. Appears to be associated with rapid metabolism of oestrogen. Takes about 2-3 years at age ~45.

Type III - Mechanism appears to be "perfect storm" of two common mutations, triggered by administration of a statin. Takes about 3 MONTHS at age ~45. One known case - me

Type IV - No details yet, but case is in her teens.

Still nothing on PubMed. There's good reason to think this is severely under-reported, especially if it affects men (and that would usually be fatal, I think).